Department of Computer Science, Key Laboratory of Intelligent Manufacturing Technology of Ministry of Education, Shantou University, Shantou, 515000, China. Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. Clinical Research Center, Hainan Provincial Hospital of Traditional Chinese Medicine, Haikou, 570100, China. Department of Clinical Laboratory, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Guangdong Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou, 510000, China. Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA. FANX@ccf.org. Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, 510000, China. fangjs@gzucm.edu.cn.